Oxybutynin Hydrochloride for Use in Children

Oxybutynin is a medicine used to treat symptoms of an overactive bladder. This can include a sudden or urgent need to wee (urinary urgency), needing to wee more often (urinary frequency) and bedwetting (Primary Nocturnal Enuresis).

What is Oxybutynin Hydrochloride?

Oxybutynin Hydrochloride is also known as Ditropan, Cystrin and Lyrinel XL. Oxybutynin is available in tablet form. Oxybutynin works by relaxing the bladder muscles.

Oxybutynin tends to work more effectively in children with:

• bladder hyperactivity/instability

• low functioning bladder capacity

Oxybutynin should be used together with bladder re-training and support from the paediatric continence team.

Dosage

Oxybutynin should only be used in children aged 5 years and over.

The dosage is:

• 2.5mg to 3mg twice a day. The last dose should be given before bed.

If there is no response, the dose may be increased to:

• 5mg two to three times a day. The last dose should be given before bed.

Modified release Oxybutynin (Lyrinel XL 5mg and 10mg tablets) dosage is:

• 5mg once daily increased by 5mg adjusted according to your child’s response every week until a maximum dose of 15mg is given.

Further Advice

Children should be reviewed regularly while they are taking Oxybutynin.  Oxybutynin may take up to 4 weeks to reach its full effect. This review will take place within a nurse led clinic appointment.

It is important to make sure that your child brushes their teeth very regularly.  Oxybutynin reduces the saliva produced and tends to make the mouth dry.  As saliva is necessary to protect teeth from decay, it is a good idea to pay extra attention to them.

Always read the patient information leaflet included with the medication.

Reference

• Oxybutynin Hydrochloride (NICE)
  https://bnfc.nice.org.uk/drugs/oxybutynin-hydrochloride/

Contact numbers

North Tees and Hartlepool NHS Foundation Trust

Children’s Service Hub
Children’s Continence Team
Telephone: 01429 522 417
Monday to Friday, 09:00 a.m. to 05:00 p.m.

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